Vol. 7, Issue 7, Part A (2025)

Prebiotic fibers such as inulin, fructooligosaccharides (FOS), galactooligosaccharides (GOS), resistant starch, and arabinoxylans play a vital role in maintaining gut health and immune function by promoting beneficial gut microbiota and producing short-chain fatty acids (SCFAs). This paper examines the influence of agronomic practices including fertilization, irrigation, crop rotation, tillage, and organic farming on the prebiotic fiber content in crops and the resulting effects on human health. Evidence shows that sustainable practices can enhance fiber biosynthesis and soil microbial diversity, enriching crops with health-promoting fibers. These prebiotics modulate microbiota composition, increase SCFA production (notably butyrate), and regulate immune pathways, including T-regulatory cell development and inflammation control. However, variability in individual microbiota composition and gaps in interdisciplinary research hinder consistent outcomes. Future directions emphasize the need for biofortification, breeding fiber-rich crops, standardizing fiber quantification, and integrating agronomic inputs into nutritional policy to achieve personalized, health-driven agricultural systems.