In India, more than 65% people live in rural areas. Majority of the rural population suffers under nutrition or malnutrition as the Indian diet is deficient in nutrition. Sugarcane juice contains high amount of Vitamin B1, Vitamin B2, Vitamin B6, Vitamin C and inorganic salts such as iron, phosphorus, calcium and organic acids such as fumaric acid, succinic acid, citric acid and malic acid. It can be consumed as an energy drink, prevent cancer-especially prostate and breast cancer as flavonoids in sugarcane juice inhibits the growth of cancer cells in the milk glands and safe against pregnancy. Jaggery contains lot of vitamins (Vitamin A, B1, B2, B5, B6, C, D2 etc), minerals (Calcium, magnesium, phosphorus, iron, manganese, zinc etc), protein, energy etc. It is popularly known as the “Medicinal Sugar”. It has been used as a sweetener in Ayurvedic medicine for 3000 years. Indian Ayurvedic medicine considers jaggery to be beneficial in treating throat and lung infections. Huge migrant labourers back to their home in lockdown situation after losing their jobs. So, unemployment problem is a major issue in current pandemic situation. To resolve the issues of unemployment and immunity, the current article briefly describe about the potentiality of sugarcane juice and jaggery in creating employment coupled with boosting up the immunity in COVID-19 pandemic situation and its business, which are most appropriate for major portion of West Bengal as well as in India particularly in the rural areas to support the rural health and economy for sustainable development.